Biochemical evaluation of Ceiba pentandra leaf on the amelioration of testosterone induced-benign prostatic hyperplasia in Wister rats

Benign prostatic hyperplasia (BPH) is a considerable public health problem prevalent among older men. Despite its eminent prevalence, the etiology of BPH not well understood. Accumulating evidence indicates that modifiable risk factors cardiovascular disease may also increase and potentially contribute to development. This study evaluated ameliorative effect Ceiba pentandra leaf on some lipids profile indices bilirubin concentration rats induced BPH. Thirty six Wistar were divided randomly into groups (n = 6). All experimental except normal control benign using testosterone propionate estradiol valerate at dose 400 µg 80 respectively, for 21 days. After induction, in negative (BPH Control) group received no treatment. Rats standard finasterides (1mg/kg body weight), while low extract, medium extract high plant according their weights kilogram 500 mg/kg, 1000 1500 mg/kg respectively. Normal Control only feed without any special The animals all allowed access water ad libitum 28 anaesthetized after treatment period. Blood samples collected serum harvested analyses methods. Result showed had analyzed.